With that in mind, the more time you can take to visit these destinations, the better. You are probably reading this because you want to see the Grand Canyon and Antelope Canyon but you have little time. Hike Out to Horseshoe Bend in the Afternoon.Tour Upper Antelope Canyon around 11 AM, 9AM or 3PM if touring Lower Antelope Canyon.In the morning, depart for Antelope Canyon.Stay Overnight inside the Grand Canyon Village.Tour Grand Canyon National Park in the Afternoon.Here is our preferred itinerary for a two-day trip to these locations. Be aware that spending two days to see them is still going to put you on a tight schedule, you will get up early, get in late, and have a lot of driving to do.īecause of the threat of large animals on the road, it is best to avoid driving at night. A much better alternative to the above sleep-deprived dash through the desert is to spend an extra day and stay overnight in Arizona before coming back to Las Vegas.